Schizophrenia Online Chat Room 6.0
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:::: Schizophrenia Newsletter - September 12, 2010 ::::
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The final version of Schizophrenia Online Chat Room 6.0
has been released!
You can download it from the following websites:
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:::: Schizophrenia Newsletter - September 5, 2010 :::::
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WARNING : Don't Trust the Internet. Ask a Real Doctor!
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::: Schizophrenia and Stress ::::::::::::::::::::::::::
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The more we learn about stress, the more we understand
how great a role it plays in a wide range of diseases
and conditions. Not surprisingly, this is especially
true of psychiatric problems such as psychosis,
depression and alcoholism.
Stress seems to be particularly harmful for those
suffering from the psychiatric disorder schizophrenia.
This increased susceptibility to stress fits the current
thinking that schizophrenia is fundamentally related to
a combination of difficulty in filtering out what is
happening in the outside world and misattribution of
internal thoughts and feelings, along with an inability
or lessened ability to interpret social cues, all of
which make it difficult for individuals with
schizophrenia to cope.
There is a growing body of evidence supporting the idea
that stress and schizophrenia are closely linked.
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::: New Schizophrenia Drug ::::::::::::::::::::::::::::
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Drug (brand/generic) ::: LY2140023
Company/licensee ::::::: Eli Lilly
Therapy class :::::::::: Glutamate agonist
Product description :::: Reduces presynaptic release
of glutamate
Current indication ::::: Schizophrenia
Development status ::::: phase II
Eli Lilly and Co. announced that it developed a new
schizophrenia drug which doesn't have the unpleasant
side effects of its current top-selling drug.
The new drug appeared devoid of certain adverse events
that are common with existing antipsychotic drugs,
including hyperprolactinaemia, extrapyramidal symptoms
and weight gain.
All currently available antipsychotic drugs block
dopamine, D2, receptors in the brain. It's considered
the primary mechanism by which they alleviate positive
symptoms of schizophrenia.
Some also act on serotonin receptors, which may
contribute to efficacy against negative symptoms.
Lilly's LY2140023 differs from established antipsychotic
drugs in that it targets glutamate rather than dopamine
or serotonin receptors.
Unlike Zyprexa, the new drug acts on certain proteins in
the brain called mGlu2/3.
There is a substantial body of evidence to suggest that
glutamate, a neurotransmitter, may also be involved in
the pathophysiology of schizophrenia.
For years, psychiatrists have known that the
psychomimetic street drug phencyclidine (PCP) can induce
symptoms almost identical to those of schizophrenia.
Psychiatrists noted PCP’s side effects as early as the
late 1950s. But they lacked the tools to determine how
PCP affected the brain until 1979, when they found that
it blocked a glutamate receptor, called the NMDA receptor,
that is at the center of the transmission of nerve
impulses in the brain.
Zyprexa causes more or less weight gain in around 90%
of its subjects and may cause diabetes.
The new drug still have to pass phase III of clinical
trials before the U.S. Food and Drug Administration
(FDA) approves it.
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::: Schizophrenia Forum :::::::::::::::::::::::::::::::
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Lately I've been having tiny spurts of anxiety and
I have no idea why. It's been going on for about two
months but I don't think it's important enough to tell
my pdoc.
I've been on Geodon 80 mg for a little over a year now,
so I don't think it's because of the meds ...
I've been having a lot of physical problems, like
little sharp pains in my chest, my chest itself will
get tight, my stomach region will ache.
Is this anything that should be taken care of or is it
as minor as I think it is?
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Dear friend, perhaps you should talk with your doc
about it. I have OCD, and when anything at all changes
in my life, whether good or bad, i tend to magnify on
it, make mountains out of mole hills. Talking with the
doc might relieve some concerns ... take care ...
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I don't have an appt. until the 30th, should I make an
emergancy appt.?
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If things are not getting better for you in a day or
two, then perhaps you should make an emergency appt.
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::: Going to the Doctor Today ? :::::::::::::::::::::::
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A lot of people complain that all psychiatrists are
good only for prescribing pills or giving injections
... and perhaps that's true.
Some people seem to want to go to the psychiatrist and
get some real counselling. They'd like to talk about
what the psychiatrist can do to help them get back to
work or at least what would be their strengths if they
tried.
I don't know whether anyone has a psychiatrist who will
help like this. Usually it's 'see the social worker?'.
But one of the men I see when I go for my appointment
says the social worker is never in when he comes for
his appointment.
The trouble with me is that I have such high anxiety
just walking in the out-patient door that by the time
the doctor says Come in ?, all I want to do is get out
of there!
So it's a case of him saying How've you been ?? and me
saying Fine ? and then responding that way to every
question he asks me. He's trying to help but I'm about
to explode. So I guess all my psychiatrist is good for
is prescribing pills.
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:::::: Schizophrenia Newsletter - June 22, 2010 :::::::
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Panic disorder in schizophrenia.
What is a panic attack ?
A panic attack is an important attack of anxiety and
fear which occurs suddenly, sometimes without warning.
Here are some symptoms of a panic attack:
- Fear of dying.
- Fear of going crazy.
- Palpitations / thumping heart.
- Feeling dizzy, or faint.
- Chest pains.
During a panic attack you often over-breathe. If you
over-breathe you 'blow out' too much carbon dioxide
which changes the acidity in the blood.
This can make the attack seem even more frightening,
and make you over-breathe even more, and so on ...
To prevent a panic attack from getting worse, Try:
- Breathe as slowly and as deeply as you can.
Try concentrating on your breathing.
- Breathe into a paper bag. By doing this you
re-breathe your own carbon dioxide. This helps to
correct the blood acid level.
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:::::: Schizophrenia Newsletter - March 19, 2010 ::::::
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> Is Abilify really number 11 ?!
> Where are Zoloft and Prozac ?!
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Top Mental Health Medications in 2008 (U.S.A)
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1. Lexapro Depression, Anxiety 26,267,000
2. Effexor XR Depression, Anxiety 16,910,000
3. Cymbalta Depression 14,422,000
4. Seroquel Antipsychotic 11,509,000
5. Lyrica Fibromyalgia 9,845,000
6. Adderall XR ADHD medication 8,799,000
7. Topamax Anticonvulsant for bipolar 7,888,000
8. Concerta ADHD medication 7,863,000
9. Aricept Alzheimer's disease 6,214,000
10. Lamictal Anticonvulsant medication 5,601,000
11. Abilify Antipsychotic 5,221,000
12. Budeprion XL Depression 5,146,000
13. Risperdal Antipsychotic 4,633,000
14. Depakote ER Anticonvulsant 4,059,000
15. Zyprexa Antipsychotic 3,813,000
16. Namenda Alzheimer's disease 3,806,000
17. Budeprion SR Antidepressant 3,462,000
18. Suboxone Addictions 3,439,000
19. Wellbutrin XL Depression 3,301,000
20. Strattera ADHD 3,130,000
21. Vyvanse ADHD 3,088,000
22. Depakote Anticonvulsant 2,398,000
23. Geodon Oral Antipsychotic 2,319,000
24. Focalin XR ADHD 2,281,000
25. Catapres-TTS Hypertension 1,161,000
26. Paxil CR Antidepressant 1,115,000
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